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HomeConditionsAge-Related Macular Degeneration
Retinal

Age-Related Macular Degeneration

Age-Related Macular Degeneration (AMD) affects the macula, the central part of the retina responsible for sharp, detailed vision. It is a leading cause of vision loss in people over 50. AMD has two forms: dry (atrophic) which progresses slowly, and wet (neovascular) which can cause rapid, severe vision loss due to abnormal blood vessel growth.

Symptoms

Blurred or distorted central vision
Straight lines appearing wavy (metamorphopsia)
Difficulty reading or recognizing faces
Dark or empty area in the center of vision
Need for brighter light when reading
Gradual difficulty adapting to low light

Risk Factors

Age over 50 (risk increases significantly with age)
Smoking (doubles the risk)
Family history and genetic predisposition
Caucasian ethnicity
Cardiovascular disease and hypertension
Obesity and poor diet

Causes

AMD results from deterioration of the retinal pigment epithelium and photoreceptor cells in the macula. In wet AMD, abnormal blood vessels grow beneath the retina (choroidal neovascularization), leaking blood and fluid that damage the macula. The exact cause involves a combination of genetic, environmental, and aging factors.

Treatment Approaches

Anti-VEGF Injections

The primary treatment for wet AMD. Regular injections of anti-VEGF agents can stabilize or improve vision by reducing abnormal vessel growth and leakage.

Nutritional Supplements

AREDS2 formula (vitamins C, E, zinc, lutein, zeaxanthin) can slow progression of intermediate dry AMD by approximately 25%.

Monitoring

Regular OCT scans and Amsler grid self-testing help detect conversion from dry to wet AMD early, when treatment is most effective.

Prevention & Care

Do not smoke
Eat a diet rich in leafy greens and fish
Maintain healthy blood pressure and weight
Wear UV-protective sunglasses
Regular eye exams after age 50

Related Treatments

Eye Injections

Direct delivery of medication near the retina for conditions where eye drops cannot reach.

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OCT Scan

Non-invasive retinal scan providing layer-by-layer analysis of retinal structure.

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Fundus Angiography

Specialized retinal vessel imaging using fluorescent dye injection and sequential photography.

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